Protein Science

Combination of multiple alignment analysis and surface mapping paves a way for a detailed pathway reconstruction--The case of VHL (von Hippel-Lindau) protein and angiogenesis regulatory pathway

Zymogenic and enzymatic properties of the 70-80 loop mutants of factor X/Xa

Dimethyl sulfoxide at 2.5% (v/v) alters the structural cooperativity and unfolding mechanism of dimeric bacterial NAD+ synthetase

Determination of membrane protein stability via thermodynamic coupling of folding to thiol-disulfide interchange

Denaturation of replication protein A reveals an alternative conformation with intact domain structure and oligonucleotide binding activity

Crystal structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis and implications for its quaternary structure and tRNA binding

Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8

Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway

Crystal structure and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) fromStaphylococcus aureus

Critical nucleation size in the folding of small apparently two-state proteins

Cooperativity in two-state protein folding kinetics

Conformational analysis of HAMLET, the folding variant of human a-lactalbumin associated with apoptosis